Qwen on NVIDIA Ampere
Can I run Qwen2.5 72B on an RTX A6000?
Not at Q4_K_M — it needs 44.6 GB against 44.3 GB available. Drop to Q4_K_S and it fits, at about 11.9 tokens per second.
Won't fit
44.6 GB of 44.3 GB · 101%046 GB
Weights
41.2 GB
KV cache
2.5 GB
Runtime overhead
0.9 GB
Over the limit
0.3 GB
Short by 0.3 GB. You can run it with 79 of 80 layers on the RTX A6000 and the rest in system RAM, at roughly 9.90 tok/s — usable for batch work, painful for chat. A smaller quantisation or a shorter context is usually the better trade.
Generation9.90tok/s
Prompt processing217tok/s
Max context7Ktokens
KV per 1K tokens0GB
Every quantisation of Qwen2.5 72B on a RTX A6000
Highlighted row is the highest quality that still fits at 8K context.
| Quantisation | bpw | Weights | Total | Verdict | Max ctx | tok/s |
|---|---|---|---|---|---|---|
| FP16 / BF16 | 16.00 | 135.4 GB | 138.8 GB | Won't fit | — | 0.40 |
| INT8 / W8A8 | 8.50 | 71.4 GB | 74.8 GB | Won't fit | — | 1.14 |
| Q8_0 (GGUF) | 8.50 | 71.4 GB | 74.8 GB | Won't fit | — | 1.14 |
| FP8 (E4M3) | 8.00 | 67.7 GB | 71.1 GB | Won't fit | — | 1.29 |
| Q6_K | 6.56 | 55.5 GB | 58.9 GB | Won't fit | — | 2.10 |
| Q5_K_M | 5.67 | 48.0 GB | 51.4 GB | Won't fit | — | 3.67 |
| Q5_K_S | 5.52 | 46.7 GB | 50.1 GB | Won't fit | — | 4.20 |
| Q4_K_M | 4.85 | 41.2 GB | 44.6 GB | Won't fit | 7K | 9.90 |
| AWQ 4-bit | 4.25 | 39.4 GB | 42.8 GB | Fits, but tight | 13K | 11.8 |
| GPTQ 4-bit | 4.25 | 39.4 GB | 42.8 GB | Fits, but tight | 13K | 11.8 |
| MXFP4 | 4.25 | 39.4 GB | 42.8 GB | Fits, but tight | 13K | 11.8 |
| Q4_K_S | 4.58 | 39.0 GB | 42.4 GB | Fits, but tight | 14K | 11.9 |
| Q4_0 | 4.55 | 38.8 GB | 42.2 GB | Fits, but tight | 15K | 11.9 |
| IQ4_XS | 4.25 | 36.3 GB | 39.7 GB | Runs comfortably | 23K | 12.7 |
| Q3_K_M | 3.91 | 33.6 GB | 36.9 GB | Runs comfortably | 32K | 13.7 |
| IQ3_M | 3.70 | 31.8 GB | 35.2 GB | Runs comfortably | 37K | 14.4 |
| IQ3_XXS | 3.06 | 26.6 GB | 30.0 GB | Runs comfortably | 54K | 17.1 |
| Q2_K | 2.63 | 23.1 GB | 26.5 GB | Runs comfortably | 65K | 19.6 |
| IQ2_XXS | 2.06 | 18.4 GB | 21.8 GB | Runs comfortably | 80K | 24.1 |
| IQ1_M | 1.75 | 15.9 GB | 19.3 GB | Runs comfortably | 88K | 27.7 |